Clarifi ASD benefits

Health care providers

Health care providers

Clarifi ASD is a revolutionary epigenetic test, based on peer-reviewed research, that can benefit health care providers and their patients.

Clarifi ASD provides a probability score that informs clinical diagnostics. This should help health care providers make earlier diagnoses, provide more targeted referrals, and facilitate access to intervention services at younger ages.

Clarifi ASD is a biological tool that provides a probability of an autism diagnosis (0-100%). This helps identify children with autism as early as 18 months to expedite access to services.

Health care providers

More clinical application

diagnostic aid

Diagnostic aid: Clarifi ASD™ is intended to be used with children when there is a suspicion of autism (e.g. positive screening results) as early as 18 months.

collaboration

HCP collaboration: Test results can facilitate collaboration between primary care and clinicians conducting diagnostic evaluations to expedite early intervention services.

hcp toolkit

Another tool in the toolbox: Test results provide primary care and specialists biological data to complement behavioral assessments.

ref books

Insight for parents: Provides added clarity and prompts next steps toward intervention.

Diagnostic aid: Clarifi ASD™ is intended to be used with children when there is a suspicion of autism (e.g. positive screening results) as early as 18 months.

HCP collaboration: Test results can facilitate collaboration between primary care and clinicians conducting diagnostic evaluations to expedite early intervention services.

Another tool in the toolbox: Test results provide primary care and specialists biological data to complement behavioral assessments.

Insight for parents: Provides added clarity and prompts next steps toward intervention.

More clinical application

“In too many cases children may not receive a diagnosis until they are 5 years old. Early diagnosis is critical for children with autism, and primary care providers play an important role in that initial process.”

Kristin Sohl, MD, FAAP
Kristin Sohl, MD, FAAP

Associate Professor, Clinical Child Health – Vice Chair for Quality Improvement, Child Health Department – Advocacy Director, Child Health Department – Director, ECHO Autism

The Clarifi ASD story

The Clarifi ASD story

Clarifi ASD was discovered largely by chance. A pediatric resident at SUNY Upstate Medical University, experiencing challenges with the autism diagnostic process, wondered if the epigenetic research he conducted for his PhD training could be applied to autism. So he and his research professor decided to look for a correlation between epigenetic molecules in the saliva (e.g., micro RNA) and autism in children. They hoped to develop a biological test that would decrease the wait time for a final diagnosis and the start of autism specific interventions.

The pilot study, funded by the American Academy of Pediatrics (AAP), provided some unexpected and exciting results: differences in RNA features were found to accurately differentiate children with autism from their peers. This discovery led to a series of larger studies and peer-reviewed publications over the next seven years, culminating in the first ever epigenetic saliva test for autism.

The Clarifi ASD story

What’s inside the
Clarifi ASD test kit?

What’s inside the Clarifi test kit?

Each saliva test kit includes the following: a collection swab, requisition form, collection instructions, patient instructions, 4 barcode stickers, and a specimen bag.

Saliva test kit
Collection instructions
Patient instructions
Requisition form
Biospecimen bag
4 barcode stickers
Collection swab
arrowSaliva test kit
Saliva test kit The kit includes all the necessary components to administer a Clarifi test, including a prepaid UPS shipping label used to return the sample to our lab
arrowCollection instructions
Collection instructions Step-by-step instructions for the health care provider on how to properly administer the Clarifi test and ship the sample to our lab
arrowPatient instructions
Patient instructions Explains how to complete the online questionnaire, and register and pay for the kit
arrowRequisition form
Requisition form This form is completed and signed by the parent and health care provider after the test is administered Download form
arrowBiospecimen bag
Biospecimen bag

Bag used to store the saliva sample as it gets shipped to our lab

arrow4 barcode stickers
4 barcode stickers

Each kit comes with four unique barcode stickers. The health care provider will place one on the patient instructions, one on the requisition form, and two for office use

arrowCollection swab
Collection swab

This is the swab used to collect the child’s saliva

Each saliva test kit includes the following: a collection swab, requisition form, collection instructions, patient instructions, 4 barcode stickers, and a specimen bag.

What will the results report look like?

Here is the first page of a sample report. Reports are available 3 to 6 weeks after the sample is received and paid for.

What will the results report look like?

Contraindications apply

How Clarifi ASD works

How Clarifi ASD works

Here is an overview of what’s in the Clarifi ASD kit, how to administer the test, shipping the sample and receiving the test results.

How Clarifi ASD works

Here is an overview of what’s in the Clarifi ASD kit, how to administer the test, shipping the sample and receiving the test results.

Clarifi ASD is now available

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